Opportunity Information: Apply for PA 19 187
The Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33) is an NIH fellowship program designed to support experienced scientists who want to deliberately reshape their research careers. The core purpose is training: it funds a structured, mentored research experience that helps an established investigator either make a major shift in scientific direction or significantly broaden their expertise by gaining new research capabilities. The fellowship is meant to strengthen the applicant as an independent investigator in an area that aligns with the missions of participating NIH Institutes and Centers, which typically means the proposed training and research should clearly connect to NIH-relevant biomedical, behavioral, or health-related fields.
A key boundary in this announcement is how clinical trials are handled. Applicants are not allowed to propose leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial under this FOA. However, the program does allow the fellow to gain research experience within a clinical trial as long as the trial is led by a sponsor or co-sponsor, meaning the applicant can be trained in clinical trial-related research activities without being the person responsible for directing the trial itself. In practical terms, this positions the F33 as a mechanism for skill-building and career retooling rather than as a vehicle to launch a new applicant-led trial.
The opportunity is issued by the National Institutes of Health (NIH) as a discretionary grant program, and it falls under the broad activity category areas of education, environment, and health. It is associated with multiple CFDA numbers (93.113, 93.121, 93.233, 93.273, 93.398, 93.837, 93.838, 93.839, 93.840, 93.846, 93.866), reflecting the fact that multiple NIH Institutes and Centers may participate and support fellowships aligned with their respective missions. The funding opportunity number is PA-19-187, and the opportunity was created on February 21, 2019. The source data lists an original closing date of June 30, 2020, which suggests this particular posting had a defined submission window at that time; applicants typically need to verify current NIH submission cycles and active notices for the most up-to-date deadlines and policies.
Eligibility is broad and includes many types of U.S. institutions and organizations that can serve as the applicant organization or host environment for the fellowship, such as public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (both with and without 501(c)(3) status), for-profit organizations (other than small businesses), and small businesses, along with an "other" category that can capture additional eligible entities depending on NIH policy. The announcement also explicitly highlights additional eligible applicants and institution types that NIH wants to ensure are included, such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible agencies of the federal government, and non-domestic (non-U.S.) entities (foreign organizations). This breadth signals that NIH is open to hosting arrangements across a wide range of settings, including international organizations, as long as the training plan and research environment are strong and appropriate for the applicant's goals.
Overall, the F33 is best understood as a senior-level, individualized fellowship focused on retraining and professional growth through a mentored research experience. It is aimed at people who already have substantial research experience but need time, guidance, and a high-quality environment to pivot into a new area, add sophisticated methods, or otherwise expand their capabilities in ways that will meaningfully change or strengthen their long-term independent research trajectory in NIH-relevant fields.Apply for PA 19 187
- The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.233, 93.273, 93.398, 93.837, 93.838, 93.839, 93.840, 93.846, 93.866.
- This funding opportunity was created on 2019-02-21.
- Applicants must submit their applications by 2020-06-30. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: Ruth L. Kirschstein NRSA Individual Senior Fellowship (Parent F33) - PA-19-187
What is the Ruth L. Kirschstein NRSA Individual Senior Fellowship (Parent F33)?
The Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33) is an NIH fellowship program designed to support experienced scientists who want to deliberately reshape their research careers through a structured, mentored research and training experience.
What is the main purpose of the F33 fellowship?
The core purpose is training. The fellowship funds a structured, mentored research experience intended to help an established investigator make a major shift in scientific direction or significantly broaden their expertise by gaining new research capabilities.
Who is this fellowship intended for?
It is aimed at people who already have substantial research experience and want time, guidance, and a high-quality training environment to pivot into a new area, add sophisticated methods, or otherwise expand their capabilities in ways that meaningfully strengthen their long-term independent research trajectory.
Does the fellowship support independent research or training?
The emphasis is on training through a mentored research experience. While the fellowship supports research activities, it is positioned as a mechanism for skill-building and career retooling rather than simply funding an independent research project.
What kinds of career changes does the F33 support?
The program is designed to support either (1) a major shift in scientific direction, or (2) a significant broadening of expertise by gaining new research capabilities, methods, or experience that an established investigator does not currently have.
How should the proposed research and training align with NIH priorities?
The proposed training and research should clearly connect to NIH-relevant biomedical, behavioral, or health-related fields and align with the missions of participating NIH Institutes and Centers.
Can an applicant propose a clinical trial under this FOA?
No. Applicants are not allowed to propose leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial under this funding opportunity announcement.
Is any clinical trial-related experience allowed?
Yes. The fellow may gain research experience within a clinical trial as long as the trial is led by a sponsor or co-sponsor. In other words, the applicant can be trained in clinical trial-related research activities without being responsible for directing the trial.
What does it mean that the clinical trial must be led by a sponsor or co-sponsor?
It means the applicant is not the person responsible for running the trial. The fellowship can support a training experience that occurs in the context of an existing or externally led trial, where leadership responsibility remains with the sponsor or co-sponsor.
How is the F33 different from a mechanism to launch a new applicant-led clinical trial?
The F33 is framed as a training and retraining mechanism for experienced investigators. It allows clinical trial-related learning, but it is not meant to serve as the vehicle for initiating or directing a new clinical trial led by the applicant.
Which federal agency issues this opportunity?
This opportunity is issued by the National Institutes of Health (NIH).
What type of federal funding program is this?
It is a discretionary grant program.
What broad activity areas are associated with this opportunity?
The opportunity is listed under broad activity category areas of education, environment, and health.
What is the funding opportunity number?
The funding opportunity number is PA-19-187.
When was this opportunity created?
The opportunity was created on February 21, 2019.
What was the original closing date listed for this posting?
The source data lists an original closing date of June 30, 2020, suggesting this particular posting had a defined submission window at that time.
Should applicants rely on the June 30, 2020 closing date for current planning?
No. Applicants typically need to verify current NIH submission cycles and active notices to confirm the most up-to-date deadlines and policies.
Which NIH Institutes and Centers participate?
The opportunity is associated with multiple NIH-related CFDA numbers, which indicates that multiple NIH Institutes and Centers may participate and support fellowships aligned with their respective missions.
What CFDA numbers are associated with this opportunity?
The CFDA numbers listed are 93.113, 93.121, 93.233, 93.273, 93.398, 93.837, 93.838, 93.839, 93.840, 93.846, and 93.866.
What kinds of organizations can serve as the applicant organization or host environment?
Eligibility includes many types of U.S. institutions and organizations, including public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (with and without 501(c)(3) status), for-profit organizations (other than small businesses), small businesses, and an "other" category that may capture additional eligible entities depending on NIH policy.
Are small businesses eligible host organizations under this opportunity?
Yes. The eligibility description includes small businesses as eligible entities.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) are listed among eligible organization types, and small businesses are also separately included.
Are nonprofit organizations eligible even if they do not have 501(c)(3) status?
Yes. The announcement includes nonprofits both with and without 501(c)(3) status.
Are U.S. federal government agencies eligible?
Yes. The announcement explicitly includes eligible agencies of the federal government among highlighted eligible institution types.
Are non-U.S. (foreign) organizations eligible?
Yes. The announcement explicitly highlights non-domestic (non-U.S.) entities (foreign organizations) as eligible.
Do certain institution types receive explicit mention as eligible?
Yes. The announcement explicitly highlights several institution categories to ensure they are included, such as Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving Institutions, HBCUs, TCCUs, eligible federal agencies, and foreign organizations.
Does the breadth of eligible institutions indicate anything about possible host settings?
Yes. The eligibility breadth signals that NIH is open to hosting arrangements across a wide range of settings, including international organizations, as long as the training plan and research environment are strong and appropriate for the applicant's goals.
What is the overall goal of the F33 fellowship for an established investigator?
The overall goal is to strengthen the applicant as an independent investigator by supporting a mentored training experience that enables a meaningful pivot, expansion of expertise, or acquisition of new capabilities in NIH-relevant fields.
What is the best way to summarize what the F33 is "for"?
It is a senior-level, individualized fellowship focused on retraining and professional growth through a structured, mentored research experience, intended to reshape or strengthen an experienced scientist's long-term independent research trajectory.
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| Superfund Research Program Occupational Health and Safety Education Programs on Emerging Technologies (R25 - Clinical Trial Not Allowed) Apply for RFA ES 20 011 Funding Number: RFA ES 20 011 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $250,000 |
| Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed) Apply for PA 20 186 Funding Number: PA 20 186 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
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