Opportunity Information: Apply for CDC RFA GH19 1913
This funding opportunity, titled "Enhance the National Department of Health's Coordination and Leadership on HIV and TB Programs in South Africa under PEPFAR," is a U.S. government grant competition run by the U.S. Department of Health and Human Services through the Centers for Disease Control and Prevention (CDC). Issued as CDC RFA GH19 1913, it uses a cooperative agreement mechanism, meaning the CDC expects to play an active partnership role in guiding and supporting the work rather than simply issuing funds with minimal involvement. The overall intent is to strengthen South Africa's National Department of Health (NDoH) coordination and leadership so the country can more effectively plan, manage, and deliver comprehensive HIV and TB prevention, care, and treatment services, aligned with the President's Emergency Plan for AIDS Relief (PEPFAR).
The opportunity is grounded in the scale and complexity of South Africa's epidemics. HIV, TB, and sexually transmitted infections remain major public health and social challenges, with HIV prevalence above 19 percent among adults ages 15 to 49. South Africa also carries an outsized share of the global HIV burden, with roughly one in five people living with HIV worldwide residing in the country. The burden is not uniform; it differs by geography and across demographic groups, including by age and gender, and it disproportionately affects key and vulnerable populations. At the same time, tuberculosis remains the leading cause of death in South Africa and the country is among the highest-burden TB countries globally, highlighting the persistent overlap between HIV and TB and the way co-infection continues to drive illness and mortality.
While the description notes meaningful progress, it emphasizes that major barriers still stand in the way of epidemic control. New HIV infections remain high, many people start treatment too late, and weaknesses in linkage to care and long-term retention persist. The summary points to a treatment coverage gap, indicating that only about 75 percent of people with known HIV infection are on antiretroviral therapy (ART). These challenges are further intensified by deep structural and social factors, including the ongoing legacy of apartheid and severe income inequality, which can shape access to services, continuity of care, and overall health outcomes.
In practical terms, the NOFO is designed to support the continuation and enhancement of NDoH efforts that cut across the HIV and TB response, with an emphasis on national coordination and leadership. That framing implies work such as strengthening program planning and oversight, aligning partners and implementing agencies around national priorities, improving the performance of prevention and treatment programs, and ensuring that HIV and TB services are delivered in a more integrated and effective way. Because it is a cooperative agreement, applicants should expect substantial technical collaboration with CDC during implementation, often including joint planning, performance monitoring, and iterative improvement to address gaps in outcomes like earlier treatment initiation, stronger linkage systems, and better retention on ART, while also addressing TB-related morbidity and mortality.
From an administrative standpoint, the opportunity was posted on August 30, 2018, with an original application deadline of October 30, 2018 (electronically submitted applications due by 11:59 p.m. Eastern Time on the due date). The program is listed under CFDA number 93.067. The anticipated award profile is a single award (expected awards: 1) with an award ceiling of up to $90,000,000, reflecting a large-scale national-level investment. Eligibility is listed broadly as "Others," with further clarification referenced in the NOFO's additional eligibility information, indicating the competition may be targeted or limited depending on the specific eligibility language in the full announcement.
Overall, the grant opportunity is a large PEPFAR-supported investment intended to bolster NDoH leadership and coordination so South Africa can accelerate progress toward controlling HIV and TB. It focuses on addressing persistent gaps in prevention and care delivery, improving timely treatment initiation and continuity, and reducing the combined burden of HIV and TB in a context shaped by significant social and economic inequities.Apply for CDC RFA GH19 1913
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Enhance the National Department of Health's Coordination and Leadership on HIV and TB Programs in South Africa under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Aug 30, 2018.
- Applicants must submit their applications by Oct 30, 2018 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $90,000,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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| Strengthening Strategic Information, Program Implementation and Capacity Building in order to Reduce Morbidity and Mortality in the Republic of South Africa under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH19 1911 Funding Number: CDC RFA GH19 1911 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: $2,500,000 |
| Strengthening the Delivery of and Expanding Access to Quality Laboratory Services and Laboratory Safety in the Republic of South Africa under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH19 1919 Funding Number: CDC RFA GH19 1919 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: $8,000,000 |
| Supporting the South African National AIDS Council Trust (SANAC Trust) in the Coordination, Management, and Monitoring of the Multi-Sectoral Implementation of the National Strategic Plan (NSP) under PEPFAR Apply for CDC RFA GH19 1914 Funding Number: CDC RFA GH19 1914 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: $2,500,000 |
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