Opportunity Information: Apply for RFA HD 18 019
The grant opportunity titled "Interaction of HIV and Neurodevelopment of Children in Resource-Limited Settings: Improving Assessments (R01)" (Funding Opportunity Number RFA HD 18 019) is a National Institutes of Health (NIH) discretionary research grant that supports studies aimed at strengthening how cognitive and neurodevelopmental functioning is measured in children living in settings where resources are limited and HIV prevalence is high. The central focus is not simply on documenting outcomes, but on creating, refining, and validating practical assessment tools or related materials that can accurately evaluate children s cognitive development in real-world environments where standard testing approaches may be difficult to use or may not translate well across languages, cultures, educational backgrounds, or clinical contexts.
A key theme of this opportunity is implementation in the field, meaning the NIH is looking for research that goes beyond theoretical test development and addresses whether the tools can actually be used effectively in low-resource contexts. This can include adapting existing neurodevelopmental or cognitive assessments so they are culturally and linguistically appropriate, developing new instruments designed specifically for these environments, improving scoring methods or norms so results are interpretable for local populations, and producing supporting materials such as training manuals, administration guides, or quality control procedures that make the assessments reliable when delivered by locally available staff. Because the opportunity is framed around the interaction of HIV and child neurodevelopment, the intended application is to strengthen the science and the clinical or public health understanding of how HIV exposure or infection relates to neurocognitive outcomes, which requires dependable measurement tools that can be deployed consistently across diverse settings.
The funding mechanism is an R01, which typically supports investigator-initiated research projects and is commonly used for multi-year research programs with clearly defined aims, methods, and outcomes. The activity category is listed under Health, Income Security and Social Services, and the CFDA number associated with the opportunity is 93.865. The source information notes that an award ceiling and expected number of awards were not specified in the provided excerpt, but the opportunity was created on 2017-02-21 and had an original closing date of 2017-06-29, indicating it was a time-limited solicitation rather than a permanently open funding announcement.
Eligibility for this grant is broad and includes many types of organizations that can contribute to global health and child development research. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; and public housing authorities or Indian housing authorities. The opportunity also allows applications from nonprofit organizations both with and without 501(c)(3) status (as long as they are not institutions of higher education), for-profit organizations (other than small businesses), and small businesses, as well as other entities. In addition, the listing explicitly highlights other eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal agencies; Indian or Native American tribal governments that are not federally recognized; regional organizations; non-domestic (non-U.S.) entities, including foreign organizations; and U.S. territories or possessions. This wide eligibility reflects an intent to encourage partnerships among academic researchers, community organizations, governmental bodies, and international institutions that are positioned to design and test assessment approaches in the settings where they are most needed.
Overall, the opportunity is best understood as a targeted NIH research initiative meant to improve the measurement foundation for studies and programs addressing HIV-related risks to child brain development. By funding the development and improvement of neurodevelopmental assessment tools and ensuring they can be implemented reliably in resource-limited, high-HIV settings, the program aims to make future research findings more accurate, comparable, and actionable for clinicians, public health programs, and policymakers working to improve outcomes for children affected by HIV.Apply for RFA HD 18 019
- The National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "Interaction of HIV and Neurodevelopment of Children in Resource-Limited Settings: Improving Assessments (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865.
- This funding opportunity was created on 2017-02-21.
- Applicants must submit their applications by 2017-06-29. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled "Interaction of HIV and Neurodevelopment of Children in Resource-Limited Settings: Improving Assessments (R01)."
What is the Funding Opportunity Number?
The Funding Opportunity Number is RFA HD 18 019.
Who is the funding agency?
The funder is the National Institutes of Health (NIH).
What type of grant mechanism is used?
This opportunity uses the R01 funding mechanism, which typically supports investigator-initiated research projects with clearly defined aims, methods, and outcomes and is commonly used for multi-year research programs.
What is the main purpose of this funding opportunity?
The central purpose is to strengthen how cognitive and neurodevelopmental functioning is measured in children living in resource-limited settings where HIV prevalence is high, with an emphasis on practical tools that work in real-world conditions.
Is the focus only on documenting neurodevelopmental outcomes?
No. The focus is not simply on documenting outcomes. It is on creating, refining, and validating practical assessment tools or related materials that can accurately evaluate children’s cognitive development in settings where standard testing may be difficult to use or may not translate well.
What kinds of settings is this opportunity concerned with?
The opportunity is aimed at resource-limited settings, particularly those where HIV prevalence is high and where common assessment approaches may face barriers related to language, culture, educational background, or clinical context.
What does "implementation in the field" mean in this announcement?
It means the NIH is looking for research that goes beyond theoretical test development and directly evaluates whether assessment tools can actually be used effectively in low-resource contexts, including how reliably they can be administered in real-world environments.
What types of projects are encouraged under this opportunity?
Supported projects can include adapting existing neurodevelopmental or cognitive assessments to be culturally and linguistically appropriate, developing new instruments designed for these environments, improving scoring methods or norms so results are interpretable for local populations, and producing supporting materials that help ensure reliable use by locally available staff.
Are adaptations of existing assessment tools allowed?
Yes. The opportunity specifically includes adapting existing neurodevelopmental or cognitive assessments so they are culturally and linguistically appropriate.
Can applicants propose developing new assessment instruments?
Yes. Developing new instruments designed specifically for resource-limited, high-HIV settings is included in the scope described.
Does the opportunity support work on scoring, norms, or interpretability?
Yes. The description explicitly mentions improving scoring methods or norms so results are interpretable for local populations.
What supporting materials might be relevant for proposed projects?
The opportunity mentions deliverables such as training manuals, administration guides, or quality control procedures that help make assessments reliable when delivered by locally available staff.
How does HIV relate to the goal of this funding opportunity?
The opportunity is framed around the interaction of HIV and child neurodevelopment. The intended application is to strengthen research and clinical or public health understanding of how HIV exposure or infection relates to neurocognitive outcomes by improving the quality and consistency of measurement tools.
What is the activity category associated with this opportunity?
The activity category is listed as Health, Income Security and Social Services.
What is the CFDA number for this grant opportunity?
The CFDA number associated with the opportunity is 93.865.
When was this funding opportunity created?
The opportunity was created on 2017-02-21.
What was the original closing date?
The original closing date listed was 2017-06-29.
Is this described as a time-limited solicitation?
Yes. Based on the creation date and original closing date provided, it is described as a time-limited solicitation rather than a permanently open funding announcement.
Is the award ceiling specified in the provided information?
No. The source notes that an award ceiling was not specified in the provided excerpt.
Is the expected number of awards specified in the provided information?
No. The source notes that the expected number of awards was not specified in the provided excerpt.
Who is eligible to apply?
Eligibility is broad and includes many organization types, such as state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; and public housing authorities or Indian housing authorities.
Are nonprofit organizations eligible?
Yes. Nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education) are listed as eligible.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) are listed as eligible, and small businesses are also listed as eligible.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. The eligibility listing explicitly includes non-domestic (non-U.S.) entities, including foreign organizations.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are included in the list of eligible applicants.
Are organizations such as HBCUs, HSIs, and Tribal Colleges mentioned as eligible?
Yes. The listing highlights several categories, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly highlighted as eligible.
Are tribal governments that are not federally recognized eligible?
Yes. Indian or Native American tribal governments that are not federally recognized are included as eligible.
Are eligible federal agencies included in the eligibility list?
Yes. Eligible federal agencies are listed among the eligible applicants.
What is the overall goal of the initiative in practical terms?
The overall goal is to improve the measurement foundation for studies and programs addressing HIV-related risks to child brain development by funding assessment tools and materials that can be implemented reliably in resource-limited, high-HIV settings, making future findings more accurate, comparable, and actionable.
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| Interaction of HIV and Neurodevelopment of Children in Resource-Limited Settings: Improving Assessments (R21) Apply for RFA HD 18 020 Funding Number: RFA HD 18 020 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| Biomarkers: Bridging Pediatric and Adult Therapeutics (R21) Apply for PAR 17 169 Funding Number: PAR 17 169 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
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| Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics (R03) Apply for PAR 17 188 Funding Number: PAR 17 188 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
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| Human-Animal Interaction (HAI) Research (R03) Apply for PAR 17 230 Funding Number: PAR 17 230 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
| Human-Animal Interaction (HAI) Research (R01) Apply for PAR 17 231 Funding Number: PAR 17 231 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $499,999 |
| Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R03) Apply for PAR 17 191 Funding Number: PAR 17 191 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
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| Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R01) Apply for PAR 17 193 Funding Number: PAR 17 193 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
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| Identification of Reproductive-Tract Specific Proteins/Transcripts for the Development of Male and Female Non-Hormonal Contraceptives (R01) Apply for RFA HD 18 002 Funding Number: RFA HD 18 002 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Point of Care Technologies for the Evaluation and Management of Obstetrics, Neonatal, and Pediatric Critical Care Patients, and for Patients with Disorders of Reproductive Tract and Infertility (R43) Apply for RFA HD 18 028 Funding Number: RFA HD 18 028 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| NICHD Exploratory-Developmental Research Grant (R21) Apply for PA 17 259 Funding Number: PA 17 259 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| Promoting NICHD Areas of Research for HIV/AIDS in Maternal and Child Health (R01) Apply for PA 17 262 Funding Number: PA 17 262 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Data Coordinating Center for the NICHD Neonatal Research Network (U24) Apply for RFA HD 18 010 Funding Number: RFA HD 18 010 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
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